#lungportal-pages #lung-moa {
    margin: 0 auto;
}

#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner {
    background: #F8F8F8;
}

#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-teaser__image {
    padding: 0;
}

#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-teaser__content {
    padding: 0;
}

#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-image {
    height: 100%;
}

#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-teaser__image-desktop {
    height: 100%;
}

#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-image__image {
    height: 100%;
}

#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner .cmp-teaser__image {
    order: 2;
}

#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside {
    max-width: 1180px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
    padding-top: 30.8px;
    width: 312px;
    /* margin-bottom: 135px; */
    /* added 9 jan 2024 */
    margin-bottom: 65px;
    /* added end */
    left: 0;
}

#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
    font-family: Lexia;
    font-size: 56px;
    font-weight: 400;
    line-height: 60px;
    text-align: left;
    /*letter-spacing: 0.1px;*/
    margin-left: 0;
}

#lungportal-pages #lung-moa #lung-moa-mechanism-text-section {
    background: #D1DAE399;
    margin-top: -3px;
}

#lungportal-pages #lung-moa #mechanism-text-bg {
    max-width: 1440px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #lung-moa-mechanism-text-section #mechanism-text-bg #mechanism-text {
    max-width: 1180px;
    margin: 0 auto;
    padding: 30px 0;
}

#lungportal-pages #lung-moa #lung-moa-mechanism-text-section #mechanism-text-bg #mechanism-text p {
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
    text-align: left;
    width: 100%;
}

#lungportal-pages #lung-moa #image-haeding-first {
    max-width: 1440px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside {
    max-width: 1180px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #mechanism-of-action-heading {
    margin-bottom: 0px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #mechanism-of-action-heading h2 {
    color: #003262;
    font-family: Lexia;
    font-size: 46px;
    font-weight: 400;
    line-height: 50px;
    padding: 40px 0;
    margin-top: 0px;
    margin-bottom: 0px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside img {
    width: 100%;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #footnote-image-first {
    margin-bottom: 0px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #footnote-image-first p {
    color: var(--Colour-Tints-Graphite-100, #3C4242);
    font-family: Inter-regular;
    font-size: 12px;
    font-weight: 400;
    line-height: 20px;
    padding: 20px 0;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #lung-moa-human-immunoglobulin {
    margin-bottom: 0px;
    margin-top: 15px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #lung-moa-human-immunoglobulin p {
    color: var(--Colour-Tints-Graphite-100, #3C4242);
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
    /*padding: 20px 0 20px;*/
    padding: 4px 0 20px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes h2 {
    color: #003262;
    font-family: Lexia;
    font-size: 46px;
    font-weight: 400;
    line-height: 50px;
    padding: 0;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes {
    margin-bottom: 0px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes p {
    color: var(--Colour-Tints-Graphite-100, #3C4242);
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
    padding: 20px 0;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #section-second-footnote {
    margin-bottom: 0px;
}

#lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #section-second-footnote p {
    color: var(--Colour-Tints-Graphite-100, #3C4242);
    font-family: Inter-regular;
    font-size: 12px;
    font-weight: 400;
    line-height: 20px;
    padding: 20px 0 40px;
}

#lungportal-pages #lung-moa #potential-synergy-bg {
    background: #F8F8F8;
}

#lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside {
    max-width: 1440px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy {
    max-width: 1180px;
    margin: 0 auto;
    padding: 20px 0 40px;
}

#lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy h2 {
    color: #003262;
    font-family: Lexia;
    font-size: 26px;
    font-weight: 400;
    line-height: 34px;
    margin-top: 0;
}

#lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy p {
    color: #3C4242;
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main {
    max-width: 1180px;
    margin: 0 auto;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism {
    margin-bottom: 0px;
    padding: 20px 0 40px;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism h2 {
    color: #003262;
    font-family: Lexia;
    font-size: 46px;
    font-weight: 400;
    line-height: 50px;
    margin-top: 0px;
    padding: 40px 0 10px;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism p {
    color: #3C4242;
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #page-ro-id p {
    color: #3C4242;
    font-family: Inter-regular;
    font-size: 16px;
    font-weight: 400;
    line-height: 24px;
    padding: 20px 0 51.3px;
}

#lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #dependent-cell-mediated {
    margin-bottom: 0px;
    padding: 0px 0 20px;
}

#lungportal-pages #lung-moa #abbreviations-and-references #dependent-cell-mediated p {
    color: var(--Colour-Tints-Graphite-100, #3C4242);
    font-family: Inter-regular;
    font-size: 12px;
    font-weight: 400;
    line-height: 20px;
}

#lungportal-pages #lung-moa .cmp-accordion__icon::before {
    content: url(/content/dam/intelligentcontent/brands/az-oncology-uk/en/images/lungportal/arrow_down.svg) !important;
}

#lungportal-pages #lung-moa button#accordian-container-item-069cb32721-button span.cmp-accordion__title {
    color: #003262;
}

#lungportal-pages #lung-moa .cmp-accordion__button--expanded span.cmp-accordion__icon {
    transform: rotate(180deg);
}

#lungportal-pages #lung-moa .cmp-accordion__title {
    color: var(--Imfinzi-Dark-Blue, #003262);
    font-family: Lexia;
    font-size: 24px;
    font-weight: 400;
    line-height: 28px;
}

#lungportal-pages #lung-moa .cmp-accordion__header {
    background: #fff;
}

#lungportal-pages #lung-moa ol li {
    color: #3C4242;
    font-family: Inter-regular;
    font-size: 12px;
    font-style: italic;
    font-weight: 500;
    line-height: 20px;
    margin-bottom: 0;
}

#lungportal-pages #lung-moa p {
    color: #3C4242;
    font-family: Inter-regular;
    font-size: 12px;
    line-height: 20px;
}

#lungportal-pages #lung-moa a {
    color: #3C4242;
    text-decoration: underline;
}

#lungportal-pages #lung-moa .cmp-accordion__button {
    padding: 0.5em 0em;
}

#lungportal-pages #lung-moa .cmp-accordion__panel {
    padding: 0.75em 0em;
}

#lungportal-pages #lung-moa .link-red {
    text-decoration: underline;
    color: #AC182E;
}

#lungportal-pages #lung-moa #references ol {
    list-style: decimal;
    margin-left: 1.3rem;
    margin-bottom: 0;
}


/***********responsive css******************/
@media only screen and (max-width: 1235px) {
    #lungportal-pages #lung-moa {
        padding: 0 16px;
    }

    #lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-teaser__content,
    #lungportal-pages #lung-moa #lung-moa-mechanism-text-section {
        padding: 0 16px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner {
        margin: 0 -16px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside {
        margin: 0 0;
    }

    #lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy {
        padding: 20px 16px;
    }

    #lungportal-pages #lung-moa #potential-synergy-bg {
        margin: 0 -16px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
        margin-bottom: 126px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism-text-section {
        margin-left: -16px;
        margin-right: -16px;
    }

    #lungportal-pages #lung-moa br {
        display: block;
    }
}

@media only screen and (max-width: 991px) {
    #lungportal-pages #lung-moa {
        padding: 0px 16px;
    }

    #lungportal-pages #lung-moa h2 {
        border-top: 0px solid transparent;
    }

    /*#lungportal-pages #lung-moa #lung-moa-banner-teaser .cmp-teaser__content,*/
    /*#lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner .cmp-teaser__image{*/
    /*  width: 100%;*/
    /*}*/
    #lungportal-pages #lung-moa br {
        display: block;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #footnote-image-first {
        padding-right: 3px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes p {
        padding-right: 7px;
    }

    #lungportal-pages #lung-moa #references ol {
        padding-right: 11px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
        width: 312px;
        display: block;
        padding-top: 40px;
        margin-bottom: 80px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
        font-size: 30px;
        line-height: 40px;
        margin-bottom: 60px;
        letter-spacing: 0.1px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #lung-moa-human-immunoglobulin p {
        padding: 2px 0 20px;
    }

    /*#lungportal-pages #lung-moa #lung-moa-mechanism-text-section #mechanism-text-bg #mechanism-text p {
      padding: 0px 10px;
    }*/

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #mechanism-of-action-heading h2 {
        font-size: 26px;
        line-height: 34px;
        padding: 11px 0;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes h2 {
        font-size: 26px;
        line-height: 34px;
    }

    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism h2 {
        font-size: 26px;
        line-height: 34px;
        margin-top: 0px;
        padding: 14px 0 10px;
    }

    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #page-ro-id p {
        padding: 3px 0;
    }

    #lungportal-pages #lung-moa #potential-synergy-bg {
        margin: 0 -16px;
    }

    #lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy {
        padding: 20px 16px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #section-second-footnote p {
        font-size: 12px;
        line-height: 20px;
        padding: 0px 0 0px;
    }
}

@media only screen and (max-width: 990px) and (min-width: 767px) {
    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
        font-size: 35px !important;
        line-height: 40px !important;
        margin-bottom: 0px !important;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
        margin-bottom: 14% !important;
    }
}

@media only screen and (max-width: 1024px) and (min-width: 768px) {
    #lungportal-pages #lung-moa {
        padding: 0px 16px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
        font-size: 46px;
        line-height: 50px;
        letter-spacing: 0.1px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
        width: 312px;
        margin-bottom: 80px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #mechanism-of-action-heading h2 {
        font-size: 24px;
        line-height: 34px;
        padding: 11px 0;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes h2 {
        font-size: 24px;
        line-height: 34px;
    }

    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism h2 {
        font-size: 24px;
        line-height: 34px;
        margin-top: 0px;
        padding: 14px 0 10px;
    }

    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #page-ro-id p {
        padding: 3px 0;
    }
}

@media only screen and (max-width: 1150px) and (min-width: 1025px) {
    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
        font-size: 46px;
        line-height: 50px;
        letter-spacing: 0.1px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 p.lung-cancer-bannerLogo img {
        width: 312px;
        margin-bottom: 80px;
    }
}

@media screen and (min-width: 1600px) {
    #lungportal-pages #lung-moa #lung-moa-mechanism #lung-moa-mechanism-banner #lung-moa-mechanism-banner-inside h1 {
        font-size: 58px;
        letter-spacing: 0.1px;
    }

    #lungportal-pages #lung-moa #lung-moa-mechanism-text-section #mechanism-text-bg #mechanism-text p,
    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #lung-moa-human-immunoglobulin p,
    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes p,
    #lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy p,
    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism p,
    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #page-ro-id p {
        font-size: 18px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #mechanism-of-action-heading h2,
    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #immunomodulatory-changes h2,
    #lungportal-pages #lung-moa #structure-and-metabolism-main #structure-and-metabolism-inside #structure-and-metabolism h2 {
        font-size: 48px;
    }

    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #footnote-image-first p,
    #lungportal-pages #lung-moa #image-haeding-first #image-haeding-first-inside #section-second-footnote p,
    #lungportal-pages #lung-moa p,
    #lungportal-pages #lung-moa ol li {
        font-size: 14px;
    }

    #lungportal-pages #lung-moa #potential-synergy-bg #potential-synergy-inside #potential-synergy h2 {
        font-size: 28px;
    }

    #lungportal-pages #lung-moa .cmp-accordion__title {
        font-size: 26px;
    }
}